Investigating IGSF11: Insights into Its Role in Immune Regulation and Disease
Endocrinology Diagnostics
Key Summary of IGSF11:
Structural Overview
- Immunoglobulin superfamily protein
- Cell surface protein with membrane and cytoplasmic components
- Also known as PVRL3
Immune Response Functions
- Influences T cell activation
- Regulates immune cell interactions
- Supports cytokine production
- Controls T cell development
Autoimmunity Implications
- Associated with systemic lupus erythematosus
- Linked to rheumatoid arthritis
- Impacts immune tolerance
- Potential role in regulatory T cell development
Cancer Interactions
- Present in lung cancer and melanoma
- Influences tumor microenvironment
- Potential immune suppression mechanism
- Possible prognostic indicator
Research Potential
- Target for immune system modulation
- Promising avenue for therapeutic interventions
- Requires further investigation in disease contexts
Suitable ELISA Kits
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